Salivary microbial diversity – an investigation on possible biomarkers for polycystic ovarian syndrome from eastern India

dc.contributor.authorGhosh, Kusum
dc.contributor.authorChakraborty, Shreyoshi
dc.contributor.authorChatterjee, Diptendu
dc.contributor.authorBandyopadhyay, Arup Ratan
dc.date.accessioned2023-12-29T13:35:57Z
dc.date.available2023-12-29T13:35:57Z
dc.date.issued2023-12
dc.descriptionInstitutional Ethical Committee for Bio Medical and Health Research involving Human Participants, University of Calcutta & Secretary, UCSTA, C.U., Ref no.: CUIEC/02/15/2022-23.
dc.description.abstractIntroduction and aim. Polycystic ovarian syndrome (PCOS) is one of the major reproductive health issues, thought to be multifactorial, needs serious attention as a dual burden (health and economic) mainly for developing countries like India, due to its rapid rise (30%) in the last couple of years. Therefore, widespread and liberal screening for this disorder towards prognosis, diagnosis and intervention seems to be an urgent area of research. In this background, the present study attempts to unravel the association of salivary microbial diversity and PCOS. Material and methods. To achieve the purpose 100 clinically diagnosed PCOS individuals and 110 age matched non-PCOS participants from Bengalee Hindu caste population, West Bengal, India was considered. Obtained salivary samples were identified with 16S rDNA amplification and microbial diversity were determined by Alu I restriction enzyme digestion. Results. The present study revealed an explicit pattern of DNA fragment lengths varied between 200 bp and 225 bp in PCOs in comparison to the non-PCOS group. Conclusion. The cardinal feature of the present study as the first attempt from India envisaged, utilization of salivary microbial diversity as an additional potential and economizing biomarker for PCOS that stimulate new horizon of research in 21st century’s anthropology – the anthropology of microbes.eng
dc.description.sponsorshipThis work was supported by the University of Calcutta [Grant: BI ((65) 8 & 9].
dc.identifier.citationEuropean Journal of Clinical and Experimental Medicine T. 21, z. 4 (2023), s. 736–741
dc.identifier.doi10.15584/ejcem.2023.4.12
dc.identifier.eissn2544-1361
dc.identifier.urihttps://repozytorium.ur.edu.pl/handle/item/9502
dc.language.isoeng
dc.publisherPublishing Office of the University of Rzeszow
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Poland*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/pl/*
dc.subjectdiagnostic biomarker
dc.subjectPCOS
dc.subjectreproductive health
dc.subjectsalivary microbiome
dc.subjectwell-being
dc.titleSalivary microbial diversity – an investigation on possible biomarkers for polycystic ovarian syndrome from eastern India
dc.typearticle

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