Serum levels of vitamin D and tumour necrosis factor-alpha in adults with metabolic syndrome

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dc.contributor.authorRahamon, Sheu Kadiri
dc.contributor.authorGaniyu, Arinola
dc.contributor.authorCharles-Davies, Mabel Ayebatonyo
dc.contributor.authorAkinlade, Kehinde Sola
dc.contributor.authorOlaniyi, John Ayodele
dc.contributor.authorFasanmade, Adesoji Adedipe
dc.contributor.authorOyewole, Oyediran Emmanuel
dc.contributor.authorOwolabi, Mayowa Ojo
dc.contributor.authorAdebusuyi, Jane Roli
dc.contributor.authorHassan, Olufunke Olayemi
dc.contributor.authorAjobo, Muhammed Babatunde
dc.contributor.authorAdigun, Kehinde
dc.contributor.authorEbesunun, Maria Onomaghuan
dc.contributor.authorPopoola, Omolara Olutosin
dc.contributor.authorOmiyale, Wemimo
dc.contributor.authorAgbedana, Emmanuel Oluyemi
dc.date.accessioned2022-04-07T09:46:22Z
dc.date.available2022-04-07T09:46:22Z
dc.date.issued2021
dc.descriptionResults from this study were presented at the 11th Congress of the Federation of African Immunological Societies (FAIS).pl_PL.UTF-8
dc.description.abstractIntroduction. Reports continue to show that a significant association exists between serum vitamin D level and metabolic syndrome (MS)-associated inflammation. However, information on the serum levels of vitamin D and alterations in inflammation in different vitamin D status is presently lacking. Aim. To determine the serum levels of vitamin D and TNF-α, and assess their possible relationship with gender in individuals with MS. Material and methods. Sixty adults with MS and 40 controls were enrolled into this case-control study. Serum vitamin D and TNF-α levels were measured and participants stratified into different vitamin D status. Results. None of the participants had vitamin D deficiency and the mean vitamin D level was similar in MS compared with the controls. However, TNF-α level was significantly higher in MS compared with the controls. Serum vitamin D level had significant inverse correlation with serum TNF-α level in MS. Also vitamin D level was significantly lower while TNF-α level was significantly higher in female-MS compared with the male-MS. Conclusion. Adults with MS have elevated TNF-α level which appears to be associated with the serum level of vitamin D. Also, females with MS have low vitamin D level and this may exacerbate the MS-associated inflammation in them.pl_PL.UTF-8
dc.identifier.citationEuropean Journal of Clinical and Experimental Medicine T. 19, z. 4 (2021), s. 306–312pl_PL.UTF-8
dc.identifier.doi10.15584/ejcem.2021.4.3
dc.identifier.eissn2544-1361
dc.identifier.issn2544-2406
dc.identifier.urihttp://repozytorium.ur.edu.pl/handle/item/7580
dc.language.isopolpl_PL.UTF-8
dc.publisherWydawnictwo Uniwersytetu Rzeszowskiegopl_PL.UTF-8
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Międzynarodowe*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectinflammationpl_PL.UTF-8
dc.subjectmetabolic syndromepl_PL.UTF-8
dc.subjectvitamin Dpl_PL.UTF-8
dc.titleSerum levels of vitamin D and tumour necrosis factor-alpha in adults with metabolic syndromepl_PL.UTF-8
dc.typearticlepl_PL.UTF-8
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European Journal of Clinical and Experimental Medicine T.19, z. 4 (2021)