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Evaluation of platelet indexes as potential biomarkers of suspected pulmonary embolism

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dc.contributor.author Wójcik, Mariusz
dc.contributor.author Daszyk-Wójcik, Joanna
dc.contributor.author Skoczyński, Kamil
dc.date.accessioned 2019-07-15T11:12:09Z
dc.date.available 2019-07-15T11:12:09Z
dc.date.issued 2019
dc.identifier.citation European Journal of Clinical and Experimental Medicine T. 17, z. 2 (2019), s. 113–117 pl_PL.UTF-8
dc.identifier.issn 2544-2406
dc.identifier.uri http://repozytorium.ur.edu.pl/handle/item/4752
dc.description.abstract Introduction. Pulmonary embolism is one of the most frequent cardiovascular diseases, potentially leading to death. There is no validated biomarker with both high specificity and sensitivity. Aim. The aim of the study was to define the diagnostic importance of platelet count (PLT), mean platelet volume (MPV) and platelet distribution width (PDW) on acute pulmonary embolism. Material and methods. We retrospectively reviewed the medical records of 145 patients with clinically suspected acute pulmonary embolism admitted to the Emergency Department. Demographic data and laboratory tests were collected on admission. All patients underwent computed tomography (CT) angiography. Results. The total data of 145 patients were analyzed, including 65 patients (67±17 years; 30 men/35 women) with acute pulmonary embolism confirmed with CT and 80 patients (67±19 years; 26 men/54 women) with negative CT. The MPV did not differ between the patients with acute PE and the control group (8.0 fL [IQR: 7.6-8.4] vs. 7.9 fL [IQR: 7.4-8.7], p=0.45). There were no significant differences in PLT (220x103/mm3 [IQR: 172-274] vs. 243x103/mm3 [IQR: 186-286], p=0.12) and PDW (59.0 ± 6.9% vs. 57.2 ± 7.3%, p=0.12). Conclusions. Our results suggest that platelet indexes (at a single time point) are not a reliable diagnostic biomarkers of acute pulmonary embolism. pl_PL.UTF-8
dc.language.iso eng pl_PL.UTF-8
dc.publisher Wydawnictwo Uniwersytetu Rzeszowskiego pl_PL.UTF-8
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 Międzynarodowe *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ *
dc.subject mean platelet volume pl_PL.UTF-8
dc.subject platelet count pl_PL.UTF-8
dc.subject platelet distribution width pl_PL.UTF-8
dc.subject pulmonary embolism pl_PL.UTF-8
dc.title Evaluation of platelet indexes as potential biomarkers of suspected pulmonary embolism pl_PL.UTF-8
dc.type article pl_PL.UTF-8
dc.identifier.doi 10.15584/ejcem.2019.2.1
dc.identifier.eissn 2544-1361


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