I participated, together with my doctoral students, in an academic conference held in Brest at the end of May 2013 and dedicated to the publication anniversary of the Brest Bible that was printed in that town. My speech – as befitted the plenary session – was conceived as a general introduction to the conference part focused on the subject matter. I introduced the matter generally, but the selected topics were elaborated upon in detail by the aforementioned group of my younger colleagues. We are pleased to present their papers in the topic-oriented block below. I was also requested by the Organisers to summarise the ”celebration” of the 450th anniversary of its publication and to outline a plan for further studies on the Brest Bible, wherein I emphasized that the studies should be continued not only by the Polish academic community, but, considering the nature of the subject matter, also by contemporary Belarusian, Lithuanian and Ukrainian researchers within the scopes of their respective competences.