European Journal of Clinical and Experimental Medicine T.19, z. 1 (2021)

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http://repozytorium.ur.edu.pl/handle/item/6115

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    Fibromatosis-like spindle-cell metaplastic carcinoma of the breast – a case report
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2021) Osuchowski, Michał; Bartusik-Aebisher, Dorota; Kaznowska, Ewa; Aebisher, David
    Introduction. Metaplastic breast carcinoma is expressing epithelial and/or mesenchymal tissue within the same tumor. Aim. The aim of this study is to evaluate metaplastic breast carcinoma in a case report and literature review. Description of the case. The presented case desribes metaplastic carcinoma of the breast in 65 years old female patient. Conclusion. Fibromatosis-cell metaplastic carcinoma of the breast presents a particularly large diagnostic challenge. Malignant variants of this disease have been described in the literature.
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    Crohn’s disease – a case study
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2021) Pasternak, Grzegorz; Bartusik-Aebisher, Dorota; Aebisher, David; Filip, Rafał
    Introduction. Surgical treatment of patients with Crohn’s disease can be a big challenge, due to the high risk of complications that is associated with chronic inflammatory process, immunosuppressive, biological treatment, malnutrition, patient’s wasting or prone to recurrence of inflammatory changes. Aim. The aim of this work ist o present the case of patient underwent surgery, resection of the terminal ileum, right hemicolectomy and segmental jejunum resection. Description of the case. In this case patients with Crohn’s disease were accompanied by progressive nutritional deficiencies and cachexia. Conclusion. Crohn’s disease can lead to very severe abdominal and septic complications that require long-term treatment, repeated surgery, and open belly therapy with the use of vacuum therapy.
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    Urolithiasis due to renal dystopia and vascular anomalies
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2021) Pliszka, Anna; Kłos, Michał; Możdżeń, Klaudia; Balawender, Krzysztof
    Introduction. Variations in the urogenital vascular anomalies in the abdomen are common. However, they warrant attention due to their importance in operative, diagnostic, and endovascular procedures. Aim. The aim of this article is to show an example of a patient with rare kidney and vessels anomalies. We want to prove that those anomalies contributed to development of urolithiasis in this case. Description of the case. During dissection of abdomen in a female cadaver, unique vascular anomalies and a position disorder of both kidneys were observed. Conclusion. Vessel abnormalities were congenital and appeared simultaneously with renal dystopia. Both anomalies could contribute to stone formation and nephritis. Understanding of the urogenital anatomical variations and their relations to adjacent structures is significant during surgical and radiological procedures.
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    Metastasis of cancer from Merkel cells to the thyroid gland
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2021) Przyczyna, Piotr; Trojnar, Elżbieta; Bartusik-Aebisher, Dorota; Aebisher, David
    Introduction. Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer. Aim. Herein described is a case of hypertensive patient, after removal of Merkel cancer of the left gluteus skin (2011), after pulmonary embolism (2013), with degenerative changes of the spine and uterine myoma, chronically treated with Warfarin, because of suspected thyroid cancer. Description of the case. A 70-year-old woman case after removing Merkel cancer of the left buttock skin (2011), after pulmonary embolism (2013), with degenerative changes of the spine and uterine fibroids treated chronically with Warfarin because of suspected thyroid cancer is described. Conclusion. Increasing evidence of Merkel cell carcinoma with immunodeficiency and neoplasia, and the management and outcome of these patients requires study.
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    An aggressive locoregional orbital rhabdomyosarcoma and Li Fraumeni syndrome
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2021) Erok, Berrin; Kıbıcı, Kenan
    Introduction. Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma with 10 % of the cases occuring in the orbit. Patients often present with a rapidly developing proptosis and globe displacement. Aim. We aimed to present a very rare presentation of orbital RMS, with a giant exophytic orbital mass, a very rare presentation occuring in more advanced cases. Description of the case. A 3-year old girl presented to our hospital with a rapidly enlarging tissue like ulcerative mass. Her past medical history was remarkable with the diagnosis of embryonal rhabdomyosarcoma (RMS) and treatment with chemoradiotherapy at the age of 15 months. On magnetic resonance imaging (MRI), there was a giant heterogenously enhancing mass filling the right orbit and extending to the intracranial region. Li Fraumeni syndrome (LFS) was considered due to her sister death from neuroblastoma at an early age. Cytogenetic analysis revealed mutations of p53 gene, which supported our consideration. Conclusion. RMS is a highly malignant tumor which usually occurs sporadiacally. However, some rare syndromes are associated with increased incidence of RMS, such as LFS.