European Journal of Clinical and Experimental Medicine T.17, z. 1 (2019)
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- PozycjaCardiopulmonary exercise test performed on a football player: a case report(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Wołoszyn, FilipIntroduction. Cardiopulmonary Exercise Test (CPET) can precisely determine aerobic capacity, conjugate and independent functions of the pulmonary cardiovascular, and skeletal muscle systems. Aim. To describe CPET feedback from a high stamina professional football player. Description of the case. The test took place in course of one CPET session. The method of an individual case study was used in this research. The participant was a local team football player. According to the coaches’ opinion, this player had the best ability to perform long distance work. The test was performed using a cycle ergometer. Cardiopulmonary Exercise Test was performed with a cycle ergometer RAMP test. Conclusion. The player’s capacity is at a level that allows us to outline his results as a unique case.
- PozycjaUpper limb analysis measured by inertial measurement unit tool: a case report(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Wołoszyn, Filip; Czmil, AnnaIntroduction. This article reports differences in accurate and inaccurate forehand and backhand strokes in tennis. The tests were carried out on a professional tennis player. The duration of a stroke, the heights of the individual segments of the right upper limb and differences in the heights of the segments at the beginning and at the end of every phase of stroke were examined. Aim. The major aim of the work was to expose upper limb disparity in stokes. Description of the case report. The research tool was inertial motion sensors (IMS) based on an accelerometer, a gyroscope and a magnetometer. A professional tennis player was examined using the individual case method and kinematic analysis. Results. The analysis concerned the average time to perform forehand and backhand strokes during all phases of the stroke, i.e. preparation, acceleration and follow-through phases. The average heights of the individual upper limb segments during a stroke were also taken into account. The results of the study are meant to show how the movement of the upper limb affects the accuracy and velocity of a stroke. Conclusion. The movements of individual segments in some accurate strokes were similar to those in inaccurate strokes.
- PozycjaRapidly progressing dementia as a manifestation of the Creutzfeldt-Jakob disease: an analysis of two cases(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Bartosz, Seweryn; Leksa, Natalia; Uberman-Kluz, Dominika; Szymczak, Artur; Biesiadecki, Marek; Galiniak, SabinaIntroduction. Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative disease of the central nervous system which is caused by an infectious protein called prion. Multiple forms of CJD have been classified including sporadic (more than 90% cases), familial, iatrogenic and variant type of disease. CJD, especially in its early stages, is a highly challenging illness to diagnose. Aim. Article aims to present cases of Creutzfeldt-Jackob disease with early symptoms of rapidly progressing dementia at the initial stage of CJD. Description of the cases. This paper describes two cases of patients with suspected CJD with a history of rapidly progressive dementia admitted to the Department of Neurology, MSWiA Hospital in Rzeszów. Conclusion. Despite the fact that CJD is an incurable illness and there is no cure guaranteeing recovery, it is important to make the right diagnosis. Assay of 14-3-3 protein in cerebrospinal fluid is a sensitive and specific marker which is helpful in the diagnosis of CJD. The only relevant method of correctly confirming a diagnosis of this disease is by performing a brain biopsy.
- PozycjaSafety and efficacy of vaccinations in patients from high-risk groups: new challenges in the era of vaccine hesitancy(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Czajka, HannaIntroduction. Vaccinations are one of the most effective medical interventions that protect people against infectious diseases. It should be noted that a new vaccine licensing is always preceded by clinical trials assessing its safety and efficacy. Anti-vaccine propaganda carried out by vaccination opponents has become an international problem with a global reach. Aim. To review the literature on vaccinations of patients from high-risk groups. Material and methods. A literature review of the following databases has been conducted: EBSCO, PubMed, Science Direct, and Springer Link. Results. High-risk groups in the paediatric population include pre-term born infants, patients after stem cell transplantations, children with allergies and other chronic diseases. Vaccinations in the examined groups are generally safe and are an effective method of preventing infections. Conclusion. At a time when the level of vaccine skepticism is high and the epidemiological situation of many diseases is unstable, patients who are more susceptible to infection are particularly endangered. High level of knowledge of health care professionals and their personal positive attitude towards vaccinations are important for improving the vaccination coverage rates. In the light of measles epidemic outbreaks and an almost geometric increase in the number of pertussis cases noted recently, actions are needed to achieve herd immunity.
- PozycjaInfliximab in therapy of inflammatory bowels diseases(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Bar, Piotr; Galiniak, Sabina; Bartusik-Aebisher, Dorota; Filip, Rafał; Aebisher, DavidIntroduction. Infliximab is a monoclonal antibody that acts against tumor necrosis factor TNF-α. The drug is used in the treatment of autoimmune diseases. Aim. This article reviewed the efficacy and safety of infliximab for the treatment in severe ulcerative colitis. This review included studies that evaluated the clinical use of infliximab. Material and methods. This meta-analysis was performed according to systematic literature search of three major bibliographic databases (Scopus, PubMed, and Cochran). Results. Infliximab has been approved by the US Food and Drug Administration (FDA) as a medicine to treat Leśniowski and Crohn’s disease, ulcerative colitis, psoriasis, psoriatic arthritis, ankylosing spondylitis, and rheumatoid arthritis. However, further trials are required to compare other parameters of efficacy such as the clinical response with infliximab. Conclusion. In patients suffering from Crohn’s disease or ulcerative colitis under infliximab maintenance therapy, sustained good trough levels are associated with: better response and remission rates, more mucosal healing and less loss of response.