European Journal of Clinical and Experimental Medicine T.16, z. 3 (2018)

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  • Pozycja
    Physical fatigue measured by functional MRI
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Truszkiewicz, Adrian; Aebisher, David; Ożóg, Łukasz; Bartusik-Aebisher, Dorota
    Introduction. Physical fatigue is a physiological condition that can be measured by functional Magnetic Resonance Imaging (fMRI). Aim. Therefore, this work aims to present the research results currently reported in the scientific literature between the years 2014 and 2018 in the field of chronic fatigue syndrome using the functional MRI method. Material and methods. Analysis of literature. Results. We reviewed here the differences between temporary and chronic fatigue.
  • Pozycja
    The effect of diabetes on the connective tissue and the bone-joint system
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Chwalba, Artur; Otto-Buczkowska, Ewa
    Introduction. Diabetes is associated with a number of complications, including renal disease, peripheral neuropathy, retinopathy, and vascular events. Aim. Article presents the research results reported in the scientific literature about the influence of diabetes on connective tissue and the bone-joint system. Material and methods. Analysis of literature. Conclusion. Due to its multi-systemic nature, the development of additional manifestations, such as musculoskeletal complications, is possible including, for example diabetic osteopathy, limited joint mobility, joint disorders, and other, many of which are subclinical and correlated with the disease duration and its inadequate control. They should be recognized and treated properly, because their management improves the patients’ quality of life.
  • Pozycja
    Methods of singlet oxygen generation and detection for understanding photodynamic processes
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Ożóg, Łukasz; Aebisher, David
    Introduction. Photodynamic therapy (PDT) is a clinically approved therapeutic procedure that exerts selective cytotoxic activity toward malignant cells. Aim. Our goal is to present the PDT procedure which involves administration of a photosensitizing agent followed by irradiation at a wavelength corresponding to the absorbance band of the photosensitizer and energy transfer to ground state oxygen to generate cytotoxic singlet oxygen Material and methods. Analysis of literature. Results. In this paper we described the basics of PDT and lifetime of singlet oxygen in different media.
  • Pozycja
    The usefulness of relaxation time using MRI measurements
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Bober, Zuzanna; Aebisher, David; Truszkiewicz, Adrian; Ożóg, Łukasz; Bartusik-Aebisher, Dorota
    Introduction. Magnetic Resonance Imaging methods are now frequently used for the analysis of the diseased tissue. These methods are based on the fact that the spin-lattice, T1, and the spin-spin, T2, relaxation times are different in diseased tissue as compared to that of normal tissue. Aim. Here we present measurements of spin-lattice relaxation time T1 on a Magnetic Resonance Imaging scaner with field strength 1.5 Tesla. Material and methods. Measurements of T1 relaxation time and analysis of literature. Results. We provide procedure for measurements of T1 relaxation time with field strength 1.5 Tesla and present a discussion of current applications.
  • Pozycja
    Life quality of patients with the carpal tunnel syndrome
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Michalik Wolska, Joanna; Wolski, Dariusz; Bieńko, Marek; Radzki, Radosław P.
    Introduction. Carpal tunnel syndrome (CTS) is a neuropathy caused by pressure on the median nerve taking a course in the carpal tunnel. The characteristic symptoms of CTS are: pain, numbness, and a prickling sensation in the hand usually at night or after the physical effort. Symptoms of the disease affect patient quality of life which is desribed as a subjective estimation of life situation. Aim. The aim of this study was to assess the quality of patient life in those who suffer from carpal tunel syndrome. The studies were aimed to descripe the general quality of patient life and the effect of symptoms on individual aspects in the life of the afflicted. Materials and methods. The study sample was composed of 60 patients from rehabilitation and physiotherapy institutions located in the Lublin Voivodship (Poland). The studies were based on the questionnaries of life quality estimation dependent on health WHOQOL- BREF and EQ-5D-5L as well as on our own poll questionnaire. Conclusions. Symptoms of carpal tunel syndrome deteriorate the quality of patient life. Such patients have difficulties with daily activities. Among those examined, as many as 94.12% reported problems performing everyday actions (EQ – 5D – 5L). Difficulties with chores were reported by 86.70% of those examined. The patients with carpal tunel syndrome are less effective at work. Reduced achievements at work were reported by 73.30% of those examined, and a need for a shorter work day was reported by 60%. For 53.30%, difficulties in doing their jobs were significant; 20% of the examined had to change their profession or work station. The examined patients often experienced pain which deteriorated quality of sleep and disturbed everyday functioning. The patients were presented with serious difficulties in doing professional work.