European Journal of Clinical and Experimental Medicine T.16, z. 4 (2018)

URI dla tej Kolekcjihttp://repozytorium.ur.edu.pl/handle/item/4493

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Przeglądanie European Journal of Clinical and Experimental Medicine T.16, z. 4 (2018) według Autor "Filip, Rafał"

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  • Obrazek miniatury
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    Inflammatory bowel disease: clinical aspects
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Pasternak, Grzegorz; Aebisher, David; Filip, Rafał; Bartusik-Aebisher, Dorota
    Introduction. Inflammatory bowel disease is a complex disease which arises as a result of an interaction between environmental and genetic factors leading to immunological responses and inflammation in the intestine. Aim. To review medical approaches used in inflammatory bowel disorders. Materials and methods. An analysis of literature regarding inflammatory bowel diseases, Leśniowski-Crohn’s disease, ulcerative colitis and mataloproteinases. Results. Current evidence suggests that patients with inflammatory bowel disease may have an elevated risk of endothelial dysfunction and coronary artery disease. Over the past two decades, great advances have been made in our understanding of the interplay between the inflammatory bowel disease. Conclusions. Inflammatory bowel diseases are increasing in Europe. The diagnosis is usually confirmed by biopsies on colonoscopy.
  • Obrazek miniatury
    Pozycja
    Inflammatory bowel disease: the function of metalloproteinases
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Pasternak, Grzegorz; Aebisher, David; Filip, Rafał; Bartusik-Aebisher, Dorota
    Introduction. Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. Aim. The aim of this work was to review the current literature regarding matrix metalloproteinases. The databases such as PubMed, ScienceDirect and Springer were utilized to search the literature for relevant articles. Materials and methods. An analysis of literature. We collected information, data, and examples of the function of metalloproteinases. Results. Herein we show that metalloproteinases play a role in such processes as the immune response, angiogenesis, the epithelial barrier function, fibrosis induced by the inflammatory process, and in the process of carcinogenesis. Conclusions. Further studies on the role of metalloproteinases in the process of carcinogenesis associated with inflammatory bowel diseases are required.