Introduction and aim. The fear of contracting COVID-19, which affects human health biopsychosocially, is expected to affect the self-care management of patients with heart failure (HF). This study was conducted to investigate the relationship between perceived fear of COVID-19 and self-care management in HF patients. Material and methods. The study was conducted with 115 HF patients. “Sociodemographic characteristics form”, “Fear of COVID-19 tool” and “Nine-item European Heart Failure Self-care Behavior Scale (EHFScB Scale-9)” were used to collect data. Results. 51.3% of the participants in the study are in the 40–60 age range, 53.7% are male, 92.2% live with their family, 64.3% have a diagnosis of HF for less than 5 years. Levels of COVID-19 fear, and self-care management were found to be high in the participants who are 40 years old or younger, has higher education level, diagnosed within 1 to 3 years, received psychological support during the pandemic process, received training from doctor or nurse about COVID-19. Fear level and self-care levels were moderately positively correlated. Conclusion. During the COVID-19 pandemic, it is necessary to develop effective care strategies to identify individuals with diseases such as HF who should have high self-care management skills.