Arterial stiffness can predict cardiorespiratory fitness in type 2 diabetic patients?

Obrazek miniatury
Monteiro, Clara Italiano
Simões, Rodrigo Polaquini
Heubel, Alessandro Domingues
Silva, Claudio Donisete da
Ricci, Paula Angélica
Petronilho, Ariane
Borghi-Silva, Audrey
Mendes, Renata Gonçalves
Tytuł czasopisma
Tytuł tomu
Wydawnictwo Uniwersytetu Rzeszowskiego
Introduction and aim. Arterial stiffness (AS) has been associated with reduced cardiorespiratory fitness (CRF). The aim of this study was to verify if there is a relationship between augmentations index (AIx), as an index for AS assessment, and CRF in individuals with type 2 Diabetes Mellitus (T2DM). Material and methods. Observational cross-sectional study including 32 individuals diagnosed with T2DM who performed two evaluations: 1. Arterial stiffness assessment using SphygmoCor and 2. CRF throughout a cardiopulmonary exercise test on a treadmill ergometer. Oxycon Mobile® device was used to obtain oxygen uptake consumption at peak (V˙ O2peak); oxygen uptake efficiency slope (OUES) determined by linear regression in reason of the logarithmic transformation of the ventilation and V˙ O2 obtained every minute of exercise test. Statistical analysis comprised Pearson’s Correlation and linear regression analysis performed in SigmaPlot. Results. There was a significant correlation between AS and CRF: AIx and OUES; AIx@75 and; OUES. In linear regression, AIx was determinant for V˙ O2peak and OUES – AIx and; AIx@75 and V˙ O2peak. Conclusion. AS was associated with CRF in individuals with T2DM. These results contribute to the body of evidence linking arterial functional properties to CRF and suggests greater attention for this important index.
Słowa kluczowe
augmentation index , cardiorespiratory fitness , type 2 diabetes
European Journal of Clinical and Experimental Medicine T. 20, z. 1 (2022), s. 28–35