Paired box 8 in organogenesis and oncogenesis – a review
Wydawnictwo Uniwersytetu Rzeszowskiego
Introduction and aim. Paired box 8 (PAX-8) is a specific transcription factor known as a protein product gene that plays an essential role in organogenesis and oncogenesis. The aim of this paper was to discuss structure and function of PAX-8. The aim of this study is to determine the utility of PAX-8 in cytology effusions with metastatic tumor. Material and methods. This article is a review done in regards to discuss the role knowledge on PAX-8 especially in oncogenesis and organogenesis. Analysis of the literature. Current information about PAX-8 is presented. Conclusion. The PAX family of genes plays an important role in the formation of tissues and organs during embryonic development and in maintaining the proper functioning of certain cells after birth.
oncogenesis , organogenesis , paired box 8 , PAX-8 , transcription factor
European Journal of Clinical and Experimental Medicine T. 20, z. 1 (2022), s. 117–121