European Journal of Clinical and Experimental Medicine T.20, z. 2 (2022)

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    Food delivery rider and COVID-19 as a preventive measure – increased safety or risk?
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2022) Sookaromdee, Pathum; Wiwanitkit, Viroj
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    IgG4 related orbital/ophtalmic disease in COVID-19 after improving from critical pneumonia
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2022) Erok, Berrin; Mansuroğlu, İlknur; Keklikoğlu, Taha Oğuz; Önder, Hakan
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    The importance of electroencephalography in the diagnosis of hepatic encephalopathy due to cirrhosis – a case report
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2022) Fuksa, Katarzyna
    Introduction and aim. Hepatic encephalopathy (HE) associated with cirrhosis of the liver is a neuropsychiatric syndrome, with symptoms ranging from barely detectable changes to deep coma. It frequently occurs in the form of episodes and relapses and can be triggered by external factors. HE severity is graded according to the West Haven criteria. The aim of the study is to draw attention to the ever-important and often key role of electroencephalography in the diagnosis of hepatic encephalopathy, even in today’s era of increasingly advanced diagnostic methods. Description of the case. A 57-year-old patient, professionally active at the time, was admitted to the hospital’s Neurology Department on an emergency basis due to difficulties with standing and moving, orientation disorders and limb tremor. Conclusion. While HE pathogenesis is multifactorial, the most important factors include increased brain exposure to ammonia, intestinal dysbiosis, and endotoxemia inducing a systemic inflammatory response. Patient observation, blood laboratory tests, neuropsychological tests and neurophysiological tests (EEG and evoked potentials) play an important role in establishing the diagnosis. Treatment and secondary prevention of hepatic encephalopathy include elimination of triggers and reduction of ammonia production and improvement of its metabolism.
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    Characteristics of the health-promoting properties of Cornus mas
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2022) Nawrot, Klaudia; Polak-Szczybyło, Ewelina; Stępień, Agnieszka
    Introduction and aim. The medicinal properties of Cornus mas L. have been used in European and Asian folk medicine for many centuries in the prevention and treatment of many diseases. The high biological activity of the plant results primarily from the presence of valuable ingredients, including anthocyanins, flavonoids and iridoid compounds. The aim of the article is to present the role of bioactive ingredients present in C.mas that determine its health-promoting properties. Material and methods. Review and analysis of the scientific literature. Analysis of the literature. The summarize information about in the field of phytochemical properties and therapeutic effects, among others anticancer, antidiabetic, neuroprotective, cardioprotective and antibacterial. Conclusion. The results of many in vitro and in vivo scientific studies They indicate the possibility of the potential use of Cornelian cherry to obtain valuable nutraceutical and pharmacological substances.
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    Pathophysiology of thromboembolism in patients with COVID-19
    (Wydawnictwo Uniwersytetu Rzeszowskiego, 2022) Vityala, Yethindra; Krishna, Abhijit; Pandla, Dinesh; Priya Kanteti, Krishna; Sadhu, Jahnavi; Boddeti, Harsha Vardhan; Kintali, Tejesh; Khalid, Mohammad Shaour
    Introduction and aim. A small number of critically ill patients with coronavirus disease (COVID-19) develop thromboembolism (arterial or venous), both micro- and macrovascular complications such as deep vein thrombosis, pulmonary embolism, and pulmonary arterial thrombosis. The objective of the study is to describe the pathophysiology of venous thromboembolism in patients with COVID-19. Material and methods. In this article a narrative review regarding pathophysiology of thromboembolism in patients with COVID-19. Analysis of the literature. The development of coagulopathy is a consequence of the intense inflammatory response associated with hypercoagulability, platelet activation, and endothelial dysfunction. The pathophysiology that relates pulmonary thromboembolism (PTE) with COVID-19 is associated with a hypercoagulable state. PTE is suspected in hospitalized patients presenting dyspnea, decreased oxygen requirement, hemodynamic instability, and dissociation between hemodynamic and respiratory changes. In COVID-19-associated coagulopathy, initially, patients present with elevated levels of fibrinogen and D-dimer, with minimal changes in prothrombin time and platelet count. The main risk factor for the development of pulmonary embolism is the increase in D-dimer that is associated with the development of PTE. The administration of iodine-based contrast agent to patients with COVID-19 would affect P-creatinine and renal function, where Ultrasound is viewed as cost-effective and highly portable, can be performed at the bedside. Conclusion. Acute respiratory distress syndrome severity in patients with COVID-19 can explain PTE as a consequence of an exaggerated immune response.