Przeglądanie według Autor "Truszkiewicz, Adrian"
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Pozycja ASL (Arterial Spin Labeling) – historical and current perfusion MR methods(Wydawnictwo Uniwersytetu Rzeszowskiego, 2017) Guz, Wiesław; Bober, Zuzanna; Ożóg, Łukasz; Truszkiewicz, Adrian; Przypek, Aneta; Aebisher, David; Bartusik-Aebisher, Dorota; Urbanik, AndrzejDespite continuous scientific and technological advances in MR imaging, MR perfusion methods have not yet been widely deployed for routine clinical diagnostics. This is especially true for ASL (arterial spin labelling) methods used to evaluate cerebral perfusion. This method does not require a contrast agent, as new discoveries about gadolinium accumulation in the cerebellum and brain nucleus appear to be a valuable asset and provide the opportunity to be more widely deployed in clinical practice. The aim of this paper is to present the historical determinants of the development of MR perfusion techniques, the disadvantages and advantages and possible clinical applications and prospects of ASL development. Both historical articles published on MR in the 1990s and current research between 2006-2016 have been reviewed. The authors present in the work the MR perfusion method focusing on issues related to arterial spin labeling (ASL). Historically CASL (continuous ASL) and PCSL (pulsed ASL) techniques have been described and the pseudocontinuous ASL (pseudocontinuous ASL) 3D technique presents its technical and methodological considerations, advantages and disadvantages over previous methods. The methods of test protocol optimization and accompanying artifacts, as well as possible clinical applications and development perspectives, have been described.Pozycja Clinical application of advanced neuroimaging techniques – Magnetic Resonance Spectroscopy(Wydawnictwo Uniwersytetu Rzeszowskiego, 2017) Guz, Wiesław; Bober, Zuzanna; Ożóg, Łukasz; Truszkiewicz, Adrian; Przypek, Aneta; Aebisher, David; Bartusik-Aebisher, Dorota; Urbanik, AndrzejContinuous scientific research and the increasing saturation of the medical market in Poland implements the possibilities of using advanced MR techniques including MRS in everyday practice. This method, which has so far been used primarily for research purposes, can bring measurable benefits to patients not only in terms of clarifying diagnosis and narrowing differential diagnosis, but also monitoring the course of various diseases and their treatment. Here we present the basic principles of performing and interpreting spectroscopic spectra and possible clinical applications and development prospects of MRS. The literature reviewed both Polish and foreign articles both historically and in the past 10 years. The paper presents methodological issues related to the proper performance of magnetic resonance spectroscopy (MRS) and spectral composition and the role of major metabolites, as well as current clinical applications and directions of MRS development.Pozycja Functional MRI – how does it work?(Wydawnictwo Uniwersytetu Rzeszowskiego, 2017) Truszkiewicz, Adrian; Aebisher, David; Przypek, Aneta; Guz, Wiesław; Bartusik-Aebisher, DorotaMagnetic Nuclear Resonance (MRI) is a non-invasive tissue imaging method. This technique is based on the influence of a strong magnetic field and electromagnetic wave of strictly defined frequency on the nucleus of elements with non-zero spin. The study describes one of the variants of functional MRI, (fMRI), which has become a key technique in brain imaging. This technique has excellent spatial and temporal resolution and involves a changing signal intensity depending on the degree of oxygenation of the blood. Blood oxygenation levels are known to vary in accordance with neural activity and these differences can be used to detect brain activity. This is due to increased demand for energy and oxygen in the area of increased neural activity. The basis of this imaging is the so-called Blood Oxygenation-Level Dependent (BLOD) effect. The aim of this paper is to present the scope of fMRI as a diagnostic method in neurology and in neurosurgery. This paper presents the principles of fMRI, methods of application, research result development, and suggests areas of possible medical applications. The limitations of fMRI as a clinical tool in medical applications will also be addressed. Studies presented in this paper are based on clinical fMRI experience and a literature review.Pozycja Medicinal & Aromatic Plants(Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Domka, Wojciech; Aebisher, David; Truszkiewicz, Adrian; Bartusik-Aebisher, DorotaIntroduction. The objective of this study is to discuss the potential of plants species in medical applications. Aim. The main purpose of this study is to discuss ethnobotanically selected plants used in medicine. Materials and methods. We analysed literature and collected information, data, and examples of selected plants used in medicine. Results. The literature shows that for several decades, the properties of medicinal plants have been investigated and reported in the biomedical and pharmaceutical literature. Conclusions. This review includes studies on plants material. The properties of various plants physiology were discuuses with the option for the use in phythotherapy.Pozycja Physical fatigue measured by functional MRI(Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Truszkiewicz, Adrian; Aebisher, David; Ożóg, Łukasz; Bartusik-Aebisher, DorotaIntroduction. Physical fatigue is a physiological condition that can be measured by functional Magnetic Resonance Imaging (fMRI). Aim. Therefore, this work aims to present the research results currently reported in the scientific literature between the years 2014 and 2018 in the field of chronic fatigue syndrome using the functional MRI method. Material and methods. Analysis of literature. Results. We reviewed here the differences between temporary and chronic fatigue.Pozycja Radio Frequency MRI coils(Wydawnictwo Uniwersytetu Rzeszowskiego, 2020) Truszkiewicz, Adrian; Aebisher, David; Bober, Zuzanna; Ożóg, Łukasz; Bartusik-Aebisher, DorotaIntroduction. Magnetic Resonance Imaging (MRI) coils technology is a powerful improvement for clinical diagnostics. This includes opportunities for mathematical and physical research into coil design. Aim. Here we present the method applied to MRI coil array designs. Material and methods. Analysis of literature and self-research. Results. The coils that emit the radiofrequency pulses are designed similarly. As much as possible, they deliver the same strength of radiofrequency to all voxels within their imaging volume. Surface coils on the other hand are usually not embedded in cylindrical surfaces relatively close to the surface of the body. Conclusion. The presented here results relates to the art of magnetic resonance imaging (MRI) and RF coils design. It finds particular application of RF coils in conjunction with bore type MRI scanners.Pozycja Spektroskopia i czasy relaksacji magnetycznego rezonansu jądrowego in vitro jako narzędzie do charakterystyki nowotworów na poziomie komórkowym(2023-07-21) Truszkiewicz, AdrianNiniejsza praca jest zapisem działań mających na celu przeprowadzenie badań MR w zakresie spektroskopii oraz czasów relaksacji hodowli komórkowych. Badania był prowadzone z wykorzystanie klinicznego systemu rezonansu magnetycznego MR OPTIMA 360MR prod GEHC o sile pola magnetycznego 1.5T. W związku z ograniczeniami systemu MR koniecznym stało się stało się już na samym początku opracowanie szeregu cewek – obwodów odbiorczych które mogły by pracować z wykorzystywanym systemem i jednocześnie zapewniały by zwiększenie czułości jak również rozdzielczości prowadzonej diagnostyki. Praca przedstawia badania wybranych hodowli komórkowych oraz obszerne badanie wpływu różnych czynników na określenie czasów relaksacji. Wiele czynników znajdujących się na liście zakłócających nie występuje w codziennej praktyce MR i badaniach klinicznych przez co może zostać zbagatelizowanych czy też pominiętych co ma szczególne znaczenie w trybie in vitro. Kliniczne systemy MR pozwalają na badania hodowli komórkowych. Trzeba jednakże w pracy z nimi uwzględniać specyfikę i ograniczenia tychże systemów w łączności z charakterystyką badanych zjawiskPozycja The influence of ODM technique on the radiation dose received by patients during head CT scan(Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Sobczyk, Joanna; Pusz-Sapa, Aleksandra; Wojtasik, Aneta; Gaweł, Greta; Truszkiewicz, Adrian; Guz, WiesławIntroduction. Computed tomography (CT) is inexpensive radiological examination of high diagnostic effectiveness. However, common use of CT tests has led to increased exposure to ionizing radiation in the population. Aim. To assess the effect of organ dose modulation (ODM) technique on the radiation dose received by patients during head CT scan. Material and methods. A retrospective analysis of 120 tests in two groups of patients who had CT scans without and with ODM. Every group consisted of 60 people (30 women and 30 men in each). The ability to perform tests in two algorithms (without and with ODM) resulted from the fact that after installing the apparatus, tests were carried out using standard technique, and only then the ODM function was launched. Results. We found that during examinations with ODM, patients received a reduced dose of ionizing radiation. The mean DLP value with ODM is 9.4% lower than the mean DLP value without ODM by comparing the tests with and without contrasting agent. The mean DLP value obtained in men using ODM was 11.9% lower than the mean dose without ODM, and in women this difference was 6.6%. Conclusion. The mean DLP value received by men with ODM was by 11.9% lower than the mean dose without ODM, and in women this difference was 6.6%. Patients receive a lower dose both in tests with and without a contrasting agent compared to the tests where ODM was not used. A statistical significance of the obtained results was found.Pozycja The usefulness of relaxation time using MRI measurements(Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Bober, Zuzanna; Aebisher, David; Truszkiewicz, Adrian; Ożóg, Łukasz; Bartusik-Aebisher, DorotaIntroduction. Magnetic Resonance Imaging methods are now frequently used for the analysis of the diseased tissue. These methods are based on the fact that the spin-lattice, T1, and the spin-spin, T2, relaxation times are different in diseased tissue as compared to that of normal tissue. Aim. Here we present measurements of spin-lattice relaxation time T1 on a Magnetic Resonance Imaging scaner with field strength 1.5 Tesla. Material and methods. Measurements of T1 relaxation time and analysis of literature. Results. We provide procedure for measurements of T1 relaxation time with field strength 1.5 Tesla and present a discussion of current applications.