European Journal of Clinical and Experimental Medicine T.17, z. 2 (2019)
URI dla tej Kolekcjihttp://repozytorium.ur.edu.pl/handle/item/4751
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Przeglądanie European Journal of Clinical and Experimental Medicine T.17, z. 2 (2019) według Autor "Aebisher, David"
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Pozycja Glycosaminoglycan concentration in cancer tissue(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Bar, Piotr; Galiniak, Sabina; Bartusik-Aebisher, Dorota; Filip, Rafał; Aebisher, DavidIntroduction. Glycosaminoglycans (GAGs) play a widespread role in tissue modelling. GAG polymers may affect several receptor pathways in parallel. Aim. To present difference in concentration of GAG in healthy and cancer tissues. Material and methods. The literature search was performed nd reviewed using selected keywords. Results. We revieved the methods of detection various types of glycans measured by Magnetic Resonance Imaging. Conclusion. MRI methodology provides an efficient tool forstudy of cellular composition. The use T1 aof T2 measurements to study cancer tissue is a promising assay.Pozycja Imaging methods of early detection and screening for breast cancer. A review(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Gustalik, Joanna; Bartusik-Aebisher, Dorota; Aebisher, David; Kaznowska, EwaIntroduction. Breast cancer is the most frequent neoplasm among women. That is the reason why scientists all over the world are attempting to improve early detection methods of this particular malignancy. Aim. The most common and most widely used examination methods for screening for and detecting breast cancer is presented herein. Material and methods. This review was performed according to systematic literature search of three major bibliographic databases. Results. Available data suggest that incidence and mortality in high-resource countries has been declining whereas incidence and mortality in low-resource countries has been increasing. Conclusion. The role of a physician is to select the most suitable one for each patient in order to obtain the best result. No matter the method however, between 2005 and 2011, the 5-year relative survival was found to be 89%. This is thought to be due to both the increase in utilization of population-wide screening, as well as advances in treatment.Pozycja Neoadjuvant therapy in breast cancer – objectives and tasks(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Ostańska, Elżbieta; Bartusik-Aebisher, Dorota; Aebisher, David; Kaznowska, EwaIntroduction. Neoadiuvant therapy (NCT) in the treatment of breast cancer is employed for patients with early stage disease or with inoperable disease. NCT can decrease the tumor volume. It can facilitate breast conservation therapy. Response to NCT is a strong predictor of outcome breast cancer (BC). Direct target therapies has markedly improved the result of treatment BC. Aim. Therapy for breast cancer continues to improve. The importance of tumor burden on local control rates will be in the future. Material and methods. This analysis was performed using a systematic literature search. Results. The latest scientific reports give hope for greater safety and a better life for patients based on optimized and effective therapy. Conclusion. Currently, improving the effectiveness of breast cancer treatment is mainly related to the optimal use of classic therapeutic strategies. New classes of substances have been approved for treatment or are in advanced stages of clinical development.