Invited Lecture: To the Theoretical Substantiation of a Dynamic Developmental Factor That Integrates Life Processes: Biocosmological Aspects. 14th International Symposium on Biocosmology (14ISBC), in collaboration with the Europaischen Academie für Naturheilverfahren und Umweltmedizin (Berlin), Cracow universities and the Polish Society of Hyperthermia

The history of bio-philosophical considerations shows the methodological development of scientific research on the specificity of processes in living organisms. Such researches often are focused not only on the recognition of related life phenomena but, primarily, on searching for the cause that explains their comprehensive and intentional course. It is essential to use the language of holistic Teleology to describe these phenomena which I will be consciously using, and which is permanently eliminated by the modern scientific physicalism within the broadly understood life sciences. The history of scientific research also shows the paths of considerations and investigation of different researchers who gave the empirical facts an incorrect cognitive interpretation. It is enough e.g. to mention the misunderstanding of the Aristotelian bio-philosophy or the mechanical interpretation of organic phenomena by Wilhelm Roux or the inclusion of metaphysical elements to the interpretation of the scientific facts by Hans Driesch. Well-established experimental studies should continually focus on the casual relationship between totipotent processes in living organisms². Totipotentiality is still a key concept in biology of development and experimental facts derived from it should lead scholars to new conclusions and philosophical generalizations bringing them nearer to fuller understanding of these phenomena. Precise cognition of the relationship and potential abilities of individual cells in the living system, especially the clear definition of their targeted developmental integration, could lead to many practical solutions in regenerative medicine, e.g. it could clearly determine how to redirect pathological cancer cells to normal development. In this context, the question arises about a dynamic developmental factor that integrates life processes, e.g. during organic regeneration, which in the history of science was variously named (entelecheia-substance – Aristotle, Entelecheia – Hans Driesch, organizer – Hans Spemann, dynamic genome – Piotr Lenartowicz) and differently defined its way of acting. Presently, in science, it is going to assign the cybernetic information a leading informative role in the course of organic phenomena. However, the scientific question that arises in this context is: What ultimately substantiates the individual cells to be ultimately targeted and established under holistic development? Getting to know the programming mechanism of particular functions and cellular tasks would lead the scientists to be successful not only in regenerative medicine, but also in the area of plant regeneration and transplantation.