Przeglądanie według Temat "chronic obstructive pulmonary disease"

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Correlation of the end-tidal CO2 value with arterial blood gas parameters – evaluation of the treatment efficacy of COPD exacerbation in the emergency department
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2022-12) Çakmak, Fatma; Tekin, Erdal
Introduction and aim. Painful, invasive, and expensive arterial blood gas (ABG) analysis is required in the diagnosis, follow-up, treatment, and even discharge of patients with chronic obstructive pulmonary disease (COPD). This study aimed to compare the end-tidal carbon dioxide (ETCO2) value, which allows non-invasive, painless, low-cost, and continuous monitoring, with ABG parameters, in the evaluation of the treatment efficacy of COPD exacerbation. Material and methods. The study was prospectively conducted with patients who presented to the emergency department with COPD exacerbation. ABG analysis and ETCO2 measurement were simultaneously performed in patients with COPD exacerbation at the time of arrival and after treatment, and were statistically compared. Results. The study included a total of 216 patients, of whom 57.4% were male. The mean age of the patients was 67.3±13.9 years. The ETCO2 values of the patients at arrival and after COPD exacerbation treatment were 39.2±10 and 37.3±9, respectively, and a statistically significant difference was determined (p=0.001). The partial pressure of pCO2 values measured at arrival and after treatment were 40.85±10.54 and 38.74±9.25, respectively, and it was statistically significant (p=0.001). A strong positive and statistically significant correlation was found between the ETCO2 and pCO2 values both at arrival and after COPD exacerbation treatment (r=0.840; p<0.001 and r=0.872; p<0.001, respectively). The Bland-Altman plot was constructed for the agreement between ETCO2 and pCO2 at both evaluation times. Conclusion. ETCO2 measurement could accurately predict the pCO2 of patients with COPD at arrival and after COPD exacerbation treatment. Also, ETCO2 may be useful in cases where pCO2 cannot be used.
Predictors of hospitalization in patients presenting to emergency department with an acute exacerbation of COPD – a single-center study in Turkey
(Publishing Office of the University of Rzeszow, 2023-09) Sanalp Menekşe, Tuğba; Sert, Ekrem Taha
Introduction and aim. In this study, we evaluated parameters that might be associated with hospitalization in patients admitted to the emergency department (ED) with an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Material and methods. Patients with COPD who presented to ED due to AECOPD between January 1, 2020 and December 31, 2021 were included in the study. Patient data were obtained from the hospital database. Univariable and multivariable logistic regression methods were used to identify the relationship between hospitalization and clinical parameters. Results. The study included 237 patients divided into two groups: inpatients (n=124) and outpatients (n=113). We found significant differences between the two groups in terms of temperature, oxygen saturation, respiratory rate, C-reactive protein, white blood cell count, procalcitonin, albumin, arterial blood pH, pCO 2 , and non-invasive mechanical ventilation (NIMV) requirement. Multivariable logistic regression analysis showed that body temperature [odds ratio (OR):1.62;95% confidence interval (CI):1.21–4.91; p<0.001], oxygen saturation (OR:0.73, 95% CI:0.39-0.94, p<0.001), respiratory rate (OR:1.96; 95% CI: 1.07–6.14; p<0.001), albumin (OR:0.71; 95% CI:0.41–0.93; p=0.042), procalcitonin (OR:2.93; 95% CI:1.22–4.84; p<0.001), arterial blood pH (OR:0.78; 95% CI:0.29-0.91; p=0.038), pCO 2 (OR:2.45; 95% CI:1.24–4.65; p<0.001), and NIMV requirement (OR:2.31; 95% CI:1.41–5.13; p<0.001) were the independent predictors of hospitalization. Conclusion. Our findings may help identify patients who will require hospitalization at an early stage.
Social vulnerability and medication adherence in individuals with chronic obstructive pulmonary disease
(Publishing Office of the University of Rzeszow, 2024-12) Efil, Sevda; Bükrük, Ceren Mina; Özen, Ebru
Introduction and aim. The association between social vulnerability and medication adherence in individuals with chronic obstructive pulmonary disease is unclear. The aim of this study was to show the correlation of social vulnerability and medication adherence in individuals with chronic obstructive pulmonary disease. Material and methods. Data collection was conducted by face to face interview in November 2022 and May 2023. Social vulnerability and medication adherence were evaluated using the Social Vulnerability Scale and the Medication Adherence Report Scale respectively. Results. The mean scores of individuals with chronic obstructive pulmonary disease for social vulnerability and medication adherence were 20.02±6.69 and 22.76±3.29 respectively. Levels of social vulnerability varied according to comorbidity, hypertension, heart failure, visit to emergency service in the last three months due to COPD exacerbation, and using herbal products instead of medication (p<0.05). Mean scores for medication adherence were lower in women, never smokers, and those who used herbal products instead of medication (p<0.05). Conclusion. Having a higher level of social vulnerability is associated with worse medication adherence (r=-0.31, p<0.01). Individuals using herbal products are found to be at risk for social vulnerability and non-adherence to medication (p<0.05).