Przeglądanie według Autor "Sielwanowska, Wiktoria"

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Paroxysmal non-epileptic events vs epilepsy – what we know and where we are in medicine?
(Publishing Office of the University of Rzeszow, 2024-03) Syzdoł, Bartłomiej; Ziółkiewicz, Aleksandra; Sielwanowska, Wiktoria; Żybowska, Monika; Wilczek, Natalia; Szukała,Klaudia; Chrościńska-Krawczyk, Magdalena
Introduction and aim. Paroxysmal non-epileptic events (PNEEs) are neurological conditions that include behavioral changes or disturbances of consciousness. The aim of the article is to compare individual paroxysmal non-epileptic events disorders, to indicate differences in their clinical picture and to discuss their differential diagnosis. Material and methods. A review of the most common non-epileptic paroxysmal events is presented based on the available literature of PubMed and Google Scholar databases from 2000 to 2023. Analysis of the literature. Depending on the age of the child, the nature and type of seizures are variable. Unfortunately, epilepsy is currently overdiagnosed, which results in the inclusion of antiepileptic drugs without the need to use them. This may be related to the immaturity of the central nervous system, malfunctioning of other organs or have a psychogenic background. In most cases, they do not require pharmacological treatment. Conclusion. Paroxysmal non-epileptic events, due to the diverse and uncharacteristic clinical picture, pose a major diagnostic challenge. Because of the current overdiagnosis of epilepsy they should always bear in mind differential diagnosis. This is important because of the differences in the treatment of these disorders.
The gut microbiota in development and treatment of depression
(Publishing Office of the University of Rzeszow, 2023-12) Wilczek, Natalia; Bogucka, Julia; Brzyska, Anna; Sielwanowska, Wiktoria; Syzdoł, Bartłomiej; Piecewicz-Szczęsna, Halina
Introduction and aim. Nowadays, almost 4% of people in the world suffer from depressive disorders, and the forecasts of further increase in incidence are alarming. The disease is debilitating and can lead to suicide, and available treatments are still imperfect. The aim of the study was to review the literature and present the potential role of the gut microbiota in the development of depression and to consider the use of prebiotics and probiotics as one of the therapeutic options in this disease. Material and methods. Review of articles published on PubMed since 2015. Analysis of the literature. The available reports point to a relationship between disturbances in the composition of the intestinal flora and the development of depressive disorders. In addition, more and more studies indicate the benefits of the influence on mood and clinical improvement, observed when using psychobiotics as an adjuvant treatment of depression, as well as monotherapy. Conclusion. Further research is needed in this area, especially in humans, to gain a deeper understanding of the role of the gut microbiota in depression and the promising use of psychobiotics for its treatment.