Przeglądanie według Autor "Kaznowska, Ewa"

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Benign endotracheal tumor (hamartoma) mimicking bronchial asthma
(Publishing Office of the University of Rzeszow, 2024-09) Kaziród, Tomasz; Tokarski, Sławomir; Kaznowska, Ewa; Rzeszutko-Grabowska, Magdalena
Introduction and aim. The most common benign tumor of the lung is hamartoma. In many cases, it is a spherical tumor, located peripherally, often without clinical symptoms. Predominantly it is found accidentally during radiological examination. In some cases the tumor reaches a significant size in the lung parenchyma or in the lumen of the bronchi or trachea. Then, symptoms such as cough, dyspnea, wheezing, less commonly hemoptysis, and chest pain may occur. In addition, tumors located endobronchial or endotracheal may cause recurrent pneumonia or mimic obstructive diseases of the lower respiratory tract such as chronic obstructive pulmonary disease, or bronchial asthma. We present the case of a patient with an endotracheal tumor mimicking bronchial asthma. Description of the case. A 53-year-old male was taking bronchodilators and inhaled steroids for several months. The baseline chest radiograph showed no abnormalities. Spirometry suggested an obstruction of respiratory flow in the central or upper airways. The lack of improvement after asthma treatment required an extension of the diagnosis. Computed tomography allowed accurate visualization of the tumor lesion of the trachea, which was significantly obstructing its lumen, and resection was carried out. Conclusion. Our case demonstrates that tracheal tumors can present symptoms similar to respiratory tract diseases. In unresolved cases, spirometry and computed tomography are helpful in proper diagnosis.
Bladder Mullerianosis – a case report
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Ostańska, Elżbieta; Aebisher, David; Kaznowska, Ewa; Bartusik-Aebisher, Dorota
Introduction. Bladder mullerianosis is a rare and proliferative lesion that contains at least two types of ectopic Mullerian tissue in its wall. Aim. To present case of bladder mullerianosis. Description of case. The text contains a description of a clinical case of a 50-year-old woman admitted to a gynecological ward due to diarrheal symptoms and abdominal pain. In a CT examination of the abdominal cavity with contrast, within the posterior left-sided wall of the bladder a 43x25mm proliferative lesion suggestive of neoplastic character was revealed. Transurethral resection of the lesion (TURB) was performed. Histopathology revealed endosalpingiosis with small endocervical foci. The picture of hyperplasia met the criterion of mullerianosis. Conclusion. Bladder Mullerianosis is a very rare disease that occurs mainly in women of reproductive age. It has very good prognosis. It is important to differentiate the lesion with malignant tumor. The basis for the diagnosis is the histopathological examination of the lesion tissues taken during the surgery.
Epidemiology of breast cancer in Podkapackie voivodship
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Gustalik, Joanna; Bartusik-Aebisher, Dorota; Ostańska, Elżbieta; Przyczyna, Piotr; Osuchowski, Michał; Aebisher, David; Galiniak, Sabina; Kaznowska, Ewa
Introduction. Breast cancer is the second most prevalent reason for cancer deaths after lung cancer. Incidence rates have increased worldwide. Aim. To present epidemiology of breast cancer in Podkapackie voivodship. Material and methods. This analysis was performed using a systematic literature search. Results. In the Podkarpackie voivodship up until 2014, the incidence rate of female breast cancer was rising and in 2015 it dropped by 68 cases. Even though the survival rate is increasing, it is still one of the leading causes of cancer deaths placing second after lung cancer. Conclusion. Mortality rate, unfortunately, rose gradually. This shows that even though there is a National Health Program aiming at breast cancer awareness and prevention, it is still not enough to reduce the number of breast cancer deaths.
Fibromatosis-like spindle-cell metaplastic carcinoma of the breast – a case report
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2021) Osuchowski, Michał; Bartusik-Aebisher, Dorota; Kaznowska, Ewa; Aebisher, David
Introduction. Metaplastic breast carcinoma is expressing epithelial and/or mesenchymal tissue within the same tumor. Aim. The aim of this study is to evaluate metaplastic breast carcinoma in a case report and literature review. Description of the case. The presented case desribes metaplastic carcinoma of the breast in 65 years old female patient. Conclusion. Fibromatosis-cell metaplastic carcinoma of the breast presents a particularly large diagnostic challenge. Malignant variants of this disease have been described in the literature.
Hyalinising clear cell carcinoma of salivary gland: a case report
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2020) Osuchowski, Michał; Bartusik-Aebisher, Dorota; Kaznowska, Ewa; Aebisher, David
Introduction. Clear cell carcinoma, not otherwise specified/hyalinising clear cell carcinoma of the salivary gland (HCCC) is a malignancy that arises in minor salivary glands. It rarely leads to distant metastases or cancer-related death but has the potential for recurrence and focal metastases. Aim. A case is reported. Description of the case. A 72 years old female patient has reported to the Clinic of Otolaryngology with a tongue lesion. The patient had no history of malignancy. The lymph node has been surgically removed for further examination. Cords and nests of clear cells and cells with eosinophilic cytoplasm in a hyalinized stroma were identified within the lymph node. After the diagnosis the patient has been transferred to another Oncology Hospital for further treatment. Conclusion. The diagnosis of clear cell carcinoma may be challenging because many of it‘s features frequently overlap with other salivary gland lesions.
Imaging methods of early detection and screening for breast cancer. A review
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Gustalik, Joanna; Bartusik-Aebisher, Dorota; Aebisher, David; Kaznowska, Ewa
Introduction. Breast cancer is the most frequent neoplasm among women. That is the reason why scientists all over the world are attempting to improve early detection methods of this particular malignancy. Aim. The most common and most widely used examination methods for screening for and detecting breast cancer is presented herein. Material and methods. This review was performed according to systematic literature search of three major bibliographic databases. Results. Available data suggest that incidence and mortality in high-resource countries has been declining whereas incidence and mortality in low-resource countries has been increasing. Conclusion. The role of a physician is to select the most suitable one for each patient in order to obtain the best result. No matter the method however, between 2005 and 2011, the 5-year relative survival was found to be 89%. This is thought to be due to both the increase in utilization of population-wide screening, as well as advances in treatment.
Imaging studies of kidney cancer
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Przyczyna, Piotr; Aebisher, David; Gustalik, Joanna; Galiniak, Sabina; Bartusik-Aebisher, Dorota; Kaznowska, Ewa
Introduction. In 2017 in the USA about 5% in men and 3% in women newly diagnosed cases of malignant tumors were kidney and renal pelvis cancer. Aim. Kidney cancer in adults includes malignant tumors derived from kidney parenchyma and renal pelvis. The dominating types are kidney parenchyma, and mainly renal cell carcinomas Material and methods. This review was performed according to systematic literature search of three major bibliographic databases (Scopus, PubMed, and Cochran). Results. Imaging studies play a very important role in kidney cancer. They allow one to assess the clinical stage, justify the extent of surgery and have an impact on the prognosis. Conclusion. The field for research involves the use of magnetic resonance and positron emission tomography in diagnosing kidney changes.
Mixed adenocarcinoma-neuroendocrine cancer – a case report
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2020) Gustalik, Joanna; Aebisher, David; Kaznowska, Ewa; Bartusik-Aebisher, Dorota
Introduction. Mixed adenocarcinoma-neuroendocrine cancer (MANEC) is a rare cancer that is characterized by aggressive course and poor prognosis. Aim. A case report and literature review. Description of the case. This article presents the case of a 63-year-old patient who was hospitalized due to the occurrence of neurological symptoms such as nausea, dizziness and headache as well as double vision and numbness of the hands. Suspected ischemic stroke, meningitis with bacterial etiology or brainstem pathology. Conclusion. MANEC composed of large neuroendocrine cells have better survival and clinical behavior than patients with small, intermediate or mixed large and intermediate cells.
Multiparametric MRI and other imaging methods suitable to stage prostate carcinoma
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Osuchowski, Michał; Aebisher, David; Galiniak, Sabina; Bartusik-Aebisher, Dorota; Kaznowska, Ewa
Introduction. The role of multiparametric magnetic resonance imaging (mpMRI) in staging prostate carcinoma has been increasing over the last years. It’s high sensitivity is indispensable when diagnosing this disease. It is a very accurate imaging method that helps the physician choose the best treatment method for his patient. Aim. Assessment of mpMRI which uses both anatomic and functional imaging techniques as a method to diagnose prostatic lesions. Advantages and disadvantages of staging prostate carcinoma with the use of biparametric MRI (bpMRI). Methods. The literature search was performed. Results. MpMRI can be used in pre-operative staging of prostate cancer. The technique is accurate in diagnosing and assessment of prostate carcinoma with Gleason Score (GS) of 7 and above. It is also recommended when planning a second biopsy of the prostatic gland.
Neoadjuvant therapy in breast cancer – objectives and tasks
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Ostańska, Elżbieta; Bartusik-Aebisher, Dorota; Aebisher, David; Kaznowska, Ewa
Introduction. Neoadiuvant therapy (NCT) in the treatment of breast cancer is employed for patients with early stage disease or with inoperable disease. NCT can decrease the tumor volume. It can facilitate breast conservation therapy. Response to NCT is a strong predictor of outcome breast cancer (BC). Direct target therapies has markedly improved the result of treatment BC. Aim. Therapy for breast cancer continues to improve. The importance of tumor burden on local control rates will be in the future. Material and methods. This analysis was performed using a systematic literature search. Results. The latest scientific reports give hope for greater safety and a better life for patients based on optimized and effective therapy. Conclusion. Currently, improving the effectiveness of breast cancer treatment is mainly related to the optimal use of classic therapeutic strategies. New classes of substances have been approved for treatment or are in advanced stages of clinical development.
Primary breast angiosarcoma – a case report
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2020) Ostańska, Elżbieta; Aebisher, David; Kaznowska, Ewa; Bartusik-Aebisher, Dorota
Introduction. Angiosarcoma is a rare breast cancer that can be primary or secondary after surgery or after breast cancer radiotherapy. It is important that breast angiosarcoma belongs to tumors with a non-specific clinical and radiological picture. Aim. The study of the biopsies contained aggressive vasomotor hyperplasia. Description of the case. The presented case concerns the primary angiosarcoma of the right breast in a 56-year-old woman who had never had a surgical procedure before, nor radiotherapy in the area of the breast. Conclusion. Histopathological examination supported by immunohistochemistry is a reliable and indispensable diagnostic element in the diagnosis of vascular sarcoma.
The advancement of imaging in diagnosis of prostate cancer
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Osuchowski, Michał; Aebisher, David; Gustalik, Joanna; Bartusik-Aebisher, Dorota; Kaznowska, Ewa
Introduction. Multiple imaging methods have been used to stage prostate carcinoma. Some of them are easily accessible, others very accurate. The advancements over many years have been taken under consideration and now every imaging method has a specific role in the diagnosis of this malignancy. Aim. There are over 1,100,000 cases of prostate carcinoma diagnosed every year around the world. Imaging examinations have to be introduced to accurately stage, and therefore properly treat this disease. This review concentrates on advantages and disadvantages of different imaging methods. Material and methods. The literature search was performed. Results. Imaging methods serve specific goals. TRUS is recommended for acquiring biopsy specimen due to high accessibility and low cost of the examination. Conclusion. The best tool for staging prostate carcinoma and finding suspicious lesions when attempting second biopsy is mpMRI or bpMRI.
The use of imaging tests to obtain optimal margins in breast surgery
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2019) Ostańska, Elżbieta; Bartusik-Aebisher, Dorota; Gustalik, Joanna; Aebisher, David; Galiniak, Sabina; Kaznowska, Ewa
Introduction. The proper negative margins (R0) breadth in the breast - conserving surgery for invasive breast cancer (IBC) and ductal carcinoma in situ (DCIS) is very important. The presence positive surgical margins (R1) is associated with the necessity of reoperation. It delays the adjuvant therapy and psychologically burdens the patient. The re-operation increases the costs of treatment. The introduction of mammography (MMG) increased detection of DCIS by 20%. With the increase in malignancy, cancer detection decreases in MMG, inversely in MRI groving. Effective preoperative and intraoperative diagnosis aims to reduce the number of R1 resections. Aim. The size of the tumor next to its biology, determines the clinical course of the tumor. The accurate analysis of imaging tests is important. Material and methods. This analysis was performed using a systematic literature search. Results. Adequate surgical margins in breast cancer surgery for breast cancer have been reviewed. It is important to know if the cancer is multifocal and what the extent of the tumor is. Conclusion. The adequacy of margins is important for adjusting the volume of excision. It is avoiding unnecessary resection of healthy breast tissue. It is essential for a good cosmetic result and the local recurrence rate. The combination of breast MRI with conventional breast imaging resulted in the lover rate of the R1 resectios and the lower rate of the re-operation.
Treating kidney cancer – a review
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2020) Przyczyna, Piotr; Aebisher, David; Bartusik-Aebisher, Dorota; Kaznowska, Ewa
Introduction. Kidney cancer in the structure of registered cases was in 6th place in men and 8th in women. Aim. Understanding the molecular biology of renal cell carcinoma has made it possible to produce new diagnostic methods. Material and methods. This review was performed according to a systematic literature search. Results. Minimally invasive techniques seem to have a bright future in kidney cancer. However, they still require many clinical trials before they enter the general clinical use. Conclusion. Photodynamic therapy, thanks to research conducted in kidney cancer, will find application in cancer of other organs.