Przeglądanie według Autor "Dynarowicz, Klaudia"

Aktualnie wyświetlane 1 - 4 z 4

Cytisine parameters measured in the 1.5 Tesla magnetic field
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2020) Bober, Zuzanna; Galiniak, Sabina; Leksa, Dawid; Dynarowicz, Klaudia; Aebisher, David; Ostańska, Elżbieta; Czmil, Anna; Bar, Piotr; Bartusik-Aebisher, Dorota; Tutka, Piotr
Introduction. Cytisine, Cytisinum (C11H14N2O), is an organic chemical compound. Cytisine is heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. Aim. The aim of the study is to measure the influence of water on the form of drug in the magnetic field 1.5 Tesla. Material and methods. For this purpose, magnetic resonance imaging tests were performed to check the solubility of pure cytisine, Desmoxan tablets and Tabex capsules. Results. From a pharmacological point of view, both Desmoxan tablets and Tabex capsules should exert the same effect on the human body, this is due to the identical content of the active substance, in this case cytisine (1.5 mg). Conclusion. The differences in the results obtained may be related to additional excipients that contain medications, but it is believed that they should not have a negative impact on the action of the active substance.
Herbarium – Summer 2021
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2021) Trójniak, Julia; Dynarowicz, Klaudia
Introduction. Medicinal plants are perfectly suited to interact with biological macromolecules like proteins and nucleic acids. All sources of natural products such as plants, microorganisms, animals, etc. are therefore biochemical potential. Aim. The goal was to present a typical plant often found in abandoned places, fields, meadows in the Podkarpacie region of Poland. Medicinal plants presented here were collected in Summer 2021 close to the city Jarosław. Material and methods. Plants collected for herbarium, immediately after harvest, are laid out between paper sheets that absorb moisture. Dried plants retain the shape of individual organs and usually also the colors. As the result of our collection, in this article are presented Papaver rhoeas L., Centaurea cyanus L., Capsella bursa – pastoris L., Taraxacum officinalle F.H., Wigg Coll and Lamium album L. Analysis of the literature. The desire to summarize information for future generations and to present the writings of the classical scholars to a wide audience was the major stimulations for presenting a most popular medicinal plants to the reader. The plants most often obtained for pharmaceutical purposes include: chamomile, fennel, St. John’s wort, nettle, mint, dandelion, yarrow, marshmallow, sage, foxglove, lemon balm, dandelion, rosehip, aloe, ginseng, and milk thistle. Conclusion. The history of plants collections is well documented.
Nanomedicine – a review
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2022) Dynarowicz, Klaudia; Aebisher, David
Introduction and aim. Nanomedicine is a discipline of technology and science, the potential of which has recently fascinated scientists in the fields of physics, biotechnology, chemistry and medicine. This department deals with everything on the nano scale, i.e. on the level of individual atoms and molecules. This work presents the nano scale, i.e. on the level of individual atoms and molecules. Nanotechnology is currently one of the most popular and dynamically developing fields, not only in electronics, but above all in pharmacy and medicine. Material and methods. In this article a narrative review regarding nanomedicine. Analysis of the literature. The desire to summarize information about nanomedicine application of singlet oxygen is presented. Nanotechnology is a discipline of technology and science, the potential of which has recently fascinated scientists in the fields of physics, biotechnology, chemistry and medicine. Conclusion. The use of nanostructures is currently very efficient. The areas in which the potential of nanoparticles is constantly researched and confirmed by numerous articles are: radio- and chemotherapy, cancer diagnostics and imaging medicine (MRI and fluorescence imaging).
Naturally occurring photosensitizers and photodynamic therapy: laser or sun?
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2015) Dynarowicz, Klaudia
Introduction. Our understanding of photodynamic therapy (PDT) is crucial for the applications of this treatment. In this physical phenomenon occurs light absorption by the applied photosensitizer, which results in its excitation to higher electron levels. After activation, a series of complex physicochemical processes take place in the tissues, Aim. The aim of this study was to describe the basic naturally occurring photosensitizers used in PDT techniques. This study clarified applications of photosensitizers. Material and methods. This study was used basic information about PDT reaction and the selective destruction of the tumor by photooxidation: a photosensitizer, a light source and oxygen. The papers reviewed here are based on Medline/Pub. Analysis of the literature. Photodynamic therapy is an innovative form of treatment. This method is not a commonly used therapeutic and therapeutic tool, but a supplement to many already tested and analyzed techniques. Thanks to continuous research, this method has a wider and wider range of applications in medicine. Conclusion. The data indicates increased number of papers regarding applications of PDT in medicine.