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Rapidly progressing dementia as a manifestation of the Creutzfeldt-Jakob disease: an analysis of two cases

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dc.contributor.author Bartosz, Seweryn
dc.contributor.author Leksa, Natalia
dc.contributor.author Uberman-Kluz, Dominika
dc.contributor.author Szymczak, Artur
dc.contributor.author Biesiadecki, Marek
dc.contributor.author Galiniak, Sabina
dc.date.accessioned 2019-04-15T09:13:29Z
dc.date.available 2019-04-15T09:13:29Z
dc.date.issued 2019
dc.identifier.citation European Journal of Clinical and Experimental Medicine T. 17, z. 1 (2019), s. 89–93 pl_PL.UTF-8
dc.identifier.issn 2544-2406
dc.identifier.uri http://repozytorium.ur.edu.pl/handle/item/4529
dc.description.abstract Introduction. Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative disease of the central nervous system which is caused by an infectious protein called prion. Multiple forms of CJD have been classified including sporadic (more than 90% cases), familial, iatrogenic and variant type of disease. CJD, especially in its early stages, is a highly challenging illness to diagnose. Aim. Article aims to present cases of Creutzfeldt-Jackob disease with early symptoms of rapidly progressing dementia at the initial stage of CJD. Description of the cases. This paper describes two cases of patients with suspected CJD with a history of rapidly progressive dementia admitted to the Department of Neurology, MSWiA Hospital in Rzeszów. Conclusion. Despite the fact that CJD is an incurable illness and there is no cure guaranteeing recovery, it is important to make the right diagnosis. Assay of 14-3-3 protein in cerebrospinal fluid is a sensitive and specific marker which is helpful in the diagnosis of CJD. The only relevant method of correctly confirming a diagnosis of this disease is by performing a brain biopsy. pl_PL.UTF-8
dc.language.iso eng pl_PL.UTF-8
dc.publisher Wydawnictwo Uniwersytetu Rzeszowskiego pl_PL.UTF-8
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 Międzynarodowe *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ *
dc.subject 14-3-3 protein pl_PL.UTF-8
dc.subject brain biopsy pl_PL.UTF-8
dc.subject cerebrospinal fluid pl_PL.UTF-8
dc.subject Creutzfeldt-Jakob disease pl_PL.UTF-8
dc.subject EEG pl_PL.UTF-8
dc.subject prion pl_PL.UTF-8
dc.title Rapidly progressing dementia as a manifestation of the Creutzfeldt-Jakob disease: an analysis of two cases pl_PL.UTF-8
dc.type article pl_PL.UTF-8
dc.identifier.doi 10.15584/ejcem.2019.1.15
dc.identifier.eissn 2544-1361


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