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The significance of NGAL and KIM-1 proteins for diagnosis of acute kidney injury (AKI) in clinical practice

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dc.contributor.author Kubrak, Tomasz
dc.contributor.author Podgórski, Rafał
dc.contributor.author Aebisher, David
dc.contributor.author Gala-Błądzińska, Agnieszka
dc.date.accessioned 2018-09-19T12:46:14Z
dc.date.available 2018-09-19T12:46:14Z
dc.date.issued 2018
dc.identifier.citation European Journal of Clinical and Experimental Medicine T. 16, z. 1 (2018), s. 28–33 pl_PL.UTF-8
dc.identifier.issn 2544-2406
dc.identifier.uri http://repozytorium.ur.edu.pl/handle/item/3876
dc.description.abstract Introduction. Despite advances in medical care AKI (acute kidney injury) is associated with high morbidity and mortality. The lack of adequate early renal injury biomarkers is often a problem for an early AKI diagnosis. In recent years, numerous scientific studies have been carried out which reveal new urine and serum markers to assess the period of the kidney injury before revealing its late clinical effects. In most clinical settings, AKI is due to acute renal tubular necrosis which results in protein accumulation in urine. Determination of the concentrations of proteins such as NGAL (neutrophil gelatinase-associated lipocalin) and KIM-1 (kidney injury molecule-1) are of great significance in the diagnosis of AKI. Aim. The purpose of the study was to review the literature about significance of NGAL and KIM-1 proteins for diagnosis of acute kidney injury (AKI) in clinical practice. Materials and method. Analysis of Polish and foreign literature. pl_PL.UTF-8
dc.language.iso eng pl_PL.UTF-8
dc.publisher Wydawnictwo Uniwersytetu Rzeszowskiego pl_PL.UTF-8
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 Międzynarodowe *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ *
dc.subject NGAL proteins pl_PL.UTF-8
dc.subject KIM-1 proteins pl_PL.UTF-8
dc.subject acute kidney injury (AKI) pl_PL.UTF-8
dc.title The significance of NGAL and KIM-1 proteins for diagnosis of acute kidney injury (AKI) in clinical practice pl_PL.UTF-8
dc.type review pl_PL.UTF-8
dc.identifier.doi 10.15584/ejcem.2018.1.4
dc.identifier.eissn 2544-1361


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