The economic development of each voivodeship and country significantly depends on the condition of microenterprises, which function in these regions. The aim of this study was to indicate the role and importance of microenterprises in processes of regional development and shaping the local labor market. The analysis of microenterprises in the years 2010–2014 was developed on the basis of GUS data. Characteristics of the number of active enterprises and levels of remuneration were used to describe the scale of number and dynamics of changes in the business activity run by microenterprises. Conclusions: 1. In the years 2010–2014, the number of microenterprises was increasing with the exception of 2013 in Poland and 2012 in Podkarpackie Voivodeship. 2. The ratio of people employed in microenterprises per 1000 residents presented the large disparity between Poland and Podkarpackie Voivodeship. 3. Amounts of remuneration in microenterprises in the years 2010–2014 in Poland was much higher than in Podkarpackie Voivodeship.