Przeglądanie według Temat "cervical cancer"

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Evaluation of the knowledge of the issues related to human papillomavirus infections within young women
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2018) Węgorowski, Paweł; Michalik, Joanna; Turkowska, Karolina; Stanisławek, Andrzej; Wolski, Dariusz; Bieńko, Marek; Radzki, Radosław P.
Introduction. Human papillomavirus infections are frequent in on average 9% to 13% of the female population, and the risk of infection throughout life exceeds 50%. The HPV virus causes changes in the mucous membranes and the skin of the genital area in both women and men. Aim. This paper presents epidemiology, prophylaxis, diagnostics and treatment of HPV and cervical cancer infections. In addition, the knowledge of issues related to human papillomavirus infection among young women was assessed. Materials and methods. The diagnostic survey method was used to carry out the research. The research tool was a questionnaire of own authorship consisting of 41 questions. The research group consisted of 240 women. The research was carried out from June to September 2016 at the Chodźki Medical Center and the Luxmed facility in Lublin. Results. There is a relationship between the education of the respondents and their knowledge about the human papillomavirus infection. The studies did not show a significant relationship between the self-esteem of the studied women and whether they were vaccinated against the HPV virus (Chi-square = 0.362, p = 0.547). Conclusions. The general level of knowledge on issues related to human papillomavirus infection among young women is at the secondary level. A higher level of general knowledge was shown by women with better education, related to the medical and biological sciences. The self-assessment of the respondents coincides with the general knowledge, based on detailed questions, on issues related to HPV infection. Promoting knowledge about HPV infection is unsatisfactory.
Haemocytometric profile and plasma levels of selected cytokines in patients at various stages of cervical cancer
(Publishing Office of the University of Rzeszow, 2023-12) Jimoh, Mutiu Alani; Onifade, Abdulfatah Adekunle; Abbiyesuku, Fayeofori Mpakaboari; Edem, Victory Fabian; Rahamon, Sheu Kadiri; Arinola, Olatunbosun Ganiyu
Introduction and aim. Reports have shown that there is alteration in haematological and inflammatory processes in patients with cervical cancer. However, there is the dearth of information on the pattern of alteration in Nigerian patients with cervical cancer at various stages of the disease. Therefore, haemocytometric profile and plasma levels of interleukin-6 (IL-6) and IL-12 were determined in Nigerian patients with cervical cancer at various stages of the disease. Material and methods. Eighty-nine adults consisting of 49 patients with cervical cancer and 40 apparently healthy controls were enrolled into this study. Haemocytometric profile was determined using automated haematology analyzer while the plasma levels of interleukin-6 (IL-6) and IL-12 were determined using ELISA. Results. Of the participants with cervical cancer, 6.12%, 24.49%, 53.06% and 16.33% were in stages I, II, III and IV respectively. The mean plasma IL-6 level was significantly higher in patients at stage IV of the cancer compared with those in stages I, II and III. No significant differences were observed in the mean plasma IL-12 level, and the haemocytometric profile when patients in different stages of the cancer were compared with one another. Plasma IL-6 had significant positive correlation with the lymphocytes count and cancer stage but had significant negative correlation with packed cell volume (PCV), haemoglobin and total white blood cells count (WBC) in patients with cervical cancer. Conclusion. Interleukin-6 appears to play an important role in the progression of cervical cancer and could be involved in cervical cancer-associated alteration in haemocytometric profile.