Przeglądanie według Temat "body mass index"

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Association between body mass and physical activity with quality of life in patients with rheumatoid arthritis
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2017) Świtała, Anna; Wyszyńska, Justyna; Czerwińska, Kinga; Dereń, Katarzyna; Podgórska-Bednarz, Justyna; Guzik, Agnieszka
Introduction. Rheumatoid arthritis (RA) is a progressive joint condition that leads to joints destruction and complications in the internal organs and significantly affects the a patient’s functional, physical, psychological and social condition. Over the last few years, research into the quality of life (QoL) in people with chronic disease has been conducted to assess the results of treatment. Aim. The aim of the study was to assess QoL in various areas of life in regards to physical and mental functioning, social relations, and environmental influences in people with RA. Material and methods. The study group (subjects with RA) and the control group (subjects without RA) consisted of 48 people each. Subject age ranged from 19 to 68. In order to assess QoL, the WHOQOL-BREF questionnaire was used, while socio-demographic data were assessed with a questionnaire developed by the authors. Results. QoL in people with RA was lower than that of healthy individuals. The worst QoL was observed in the physical domain. No statistically significant association was found between BMI and QoL. It was found, however, that subjects with RA and a higher level of physical activity had a better QoL than those with a lower level of physical activity. Conclusion. There was no association between the body mass of RA patients and QoL assessment. However, an association was found between the level of physical activity in people with RA and QoL in the physical and environmental domain.
Clinical significance of serum interleukin-6 levels in patients with chronic kidney disease
(Publishing Office of the University of Rzeszow, 2024-09) Chokkavarapu, Renuka Charan; Bachireddy, Parimala; Billa, Vaibhavi Reddy; Vityala, Yethindra
Introduction and aim. Elevated levels of interleukin-6 (IL-6) in serum and kidney tissues are associated with the development and progression of chronic kidney disease (CKD). Although the role of pro-inflammatory cytokines, such as IL-6, in the development of cardiovascular complications is well studied, the relationship between serum IL-6 levels and CKD markers remains unclear. This study investigated the clinical significance of serum IL-6 levels in patients with CKD. Material and methods. Participants were divided into two groups based on estimated glomerular filtration rate (eGFR): group 1 (n=86) with eGFR >60 mL/min and group 2 (n=74) with eGFR <60 mL/min. The CKD Epidemiology Collaboration equation was used to calculate eGFR from serum creatinine and cystatin C levels to assess CKD severity. Results. Systolic blood pressure was higher in Group 2 than in Group 1 (138±22 mmHg vs. 129±19 mmHg; p<0.05). Serum IL-6 levels were also higher in group 2 (3.095 [interquartile range: 1.528–6.547] pg/mL) than in group 1 (1.711 [interquartile range: 0.920– 3.342] pg/mL; p <0.05). Serum IL-6 levels were strongly correlated with eGFR in multivariable-adjusted linear regression analysis. Conclusion. IL-6 levels increased in patients with CKD with an eGFR <60 mL/min, and this increase was associated with eGFR and diastolic blood pressure.
Otyłość i jej znaczenie w chorobach układu krążenia Cz. 1. Otyłość jako czynnik ryzyka
(Wydawnictwo Uniwersytetu Rzeszowskiego, 2015) Kleinrok, Andrzej
Otyłość jest stanem wynikającym z nadmiernego nagromadzenia tłuszczu w tkance tłuszczowej (tt) na podłożu genetycznym i środowiskowym. Według WHO jest definiowana jako BMI powyżej 30 kg/m2. Jest to choroba przewlekła, o zasięgu globalnym, stanowi epidemię XXI wieku. Jest czynnikiem ryzyka wielu chorób sercowo-naczyniowych (S-N), choroby wieńcowej (ChW), zawału serca (ZS), niewydolności serca (NS), udaru mózgu, zaburzeń metabolicznych, cukrzycy (DM), zespołu metabolicznego (ZM), dyslipidemii oraz powodem niepełnosprawności czy przedwczesnej śmierci. Wyróżnia się 3 fenotypy otyłości: otyłość metaboliczna z prawidłową masą ciała (MONW), otyłość androidalna (jabłko) i gynoidalna (gruszka). Mają różny przebieg, chociaż każdy z nich jest konsekwencją nierównowagi między dostarczaniem energii a jej spalaniem oraz zwykle genetycznego podłoża. Do zaburzeń S-N i metabolicznych może prowadzić MONW (jeśli się nie powstrzyma dalszego rozwoju przez właściwą dietę i aktywność fizyczną). Typ gruszki predysponuje do zwyrodnienia stawów, podczas gdy typ jabłko wiąże się z chorobami sercowymi jak ZS, udar mózgu, NT. Tkanka tłuszczowa jest narządem endokrynnym, produkującym wiele substancji aktywnych biologicznie. „Chory tłuszcz“ lub adiposopatia jest patologicznym stanem wynikającym z przewlekłego procesu zapalnego toczącego się w tt, prowadzącym do otyłości i jej patologicznych konsekwencji. Otyli pacjenci częściej i wcześniej chorują na NT, ChW, ZS, NS, zaburzenia rytmu, w tym nagły zgon sercowy (SCD). Otyłość prowadzi także do insulinooporności, dyslipidemii, ZM i ostatecznie DM t. 2. Praca jest krótkim przeglądem danych o znaczeniu otyłości jako czynnika ryzyka w chorobach krążenia.
Relationship between social media addiction and bodyweight
(Publishing Office of the University of Rzeszow, 2023-03) Tatar, Selim; Özdemir, Ayşe; Altuntaş, Zeynep Sena; Mercimekçi, Serdar; Aypak, Cenk
Introduction and aim. Social media addiction is increasing rapidly due to the widespread use of smartphones and the availability of the internet. Also, social media addiction constitutes a risk factor for many physical and mental diseases. We aimed to determine the frequency of social media addiction among obese patients. Material and methods. Adult patients who were admitted to the Diet Clinic of a tertiary healthcare hospital in order to lose weight enrolled in the study. A questionnaire including; Social Media Addiction Scale, body mass index (BMI), and demographic information (age, sex) was applied to all participants. Participants were grouped as obese, overweight, and normal weight. Results. A total of 179 patients (mean age: 34.1±12.6 years) enrolled in the study. No difference in sex was found (45.2% women, 47.3% men). Approximately half of the study population was found to be social media addicts. Participants younger than 45 years of age were found to have higher rates of social media addiction (X 2 = 4.26; p<0.05). The frequency of social media addiction was found to increase with increasing BMI (41.7%, 43.6%, and 48%; respectively). Conclusion. Social media addiction is prevalent and it is also more frequent in younger adults. Learning more about social media addiction and its relationship with obesity can decrease its health consequences.
Zinc in fibromyalgia patients: relationship with body mass index and sleep quality
(Publishing Office of the University of Rzeszow, 2022-12) Ece, Yiğit
Introduction and aim. Given the potential relationship between oxidative stress and fibromyalgia and well-documented antioxidant efficacy of zinc, the present study aimed to determine serum zinc concentration in FM patients as compared to healthy controls, as well as to identify the correlation of serum zinc concentration with the body mass index (BMI) and sleep quality, Material and methods. In this case-control study, 54 fibromyalgia patients were consecutively recruited between October 01, 2021 and December 01, 2021. The control group consisted of 54 age- and sex-matched healthy controls. Results. Fibromyalgia group had significantly lower zinc concentration, higher body mass index, and lower sleep quality scores as compared to the healthy control group. The correlation analysis revealed a significantly negative correlation between serum zinc concentration and body mass index and a significantly positive correlation between serum zinc concentration and sleep quality both in fibromyalgia and healthy control groups. Conclusion. Our results both support the hypothesis that low serum zinc concentration plays a role in the pathophysiology of fibromyalgia and indicate that fibromyalgia may lead to weight gain and poor sleep quality, which needs to be confirmed in large-cohort studies.